Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human CC2D2A
Specificity
This antibody detects endogenous levels of CC2D2A at Human, Mouse
Gene Name
CC2D2A KIAA1345
Protein Name
Coiled-coil and C2 domain-containing protein 2A
Other Name
Species
Human
Gene ID
57545
Uniprot
Q9P2K1,
Species.1
Mouse
Gene ID.1
231214
Uniprot.1
Q8CFW7
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Localizes at the transition zone, a region between the basal body and the ciliary axoneme. .
Tissue Expression
Strongly expressed in prostate, pancreas, kidney, lung, liver, retina, kidney, fetal brain and fetal kidney. Lower expression in spleen, small intestine, colon, skeletal muscle, ovary, thymus and heart.
Signaling_pathway
Research Areas
Function
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).