Price range: $268.00 through $328.00
Background:
function:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur., sequence caution:Translated as Gln., similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151.,
| Size | 50μL/100μL |
| Target | CD315 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 98kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human PTGFRN. AA range:601-650 |
| Specificity | CD315 Polyclonal Antibody detects endogenous levels of CD315 protein. |
| Gene Name | PTGFRN |
| Protein Name | Prostaglandin F2 receptor negative regulator |
| Other Name | PTGFRN; / CD9P1; / EWIF; / FPRP; / KIAA1436; / Prostaglandin F2 receptor negative regulator; / CD9 partner 1; / CD9P-1; / Glu-Trp-Ile EWI motif-containing protein F; / EWI-F; / Prostaglandin F2-alpha receptor regulatory protein; / Prostaglandin F2-alpha receptor-associated protein; / CD315 |
| Species | Human |
| Gene ID | 5738 |
| Uniprot | Q9P2B2, |
| Species.1 | Mouse |
| Gene ID.1 | 19221 |
| Uniprot.1 | Q9WV91, |
| Species.2 | Rat |
| Gene ID.2 | 29602 |
| Uniprot.2 | Q62786 |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein . Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein . |
| Tissue Expression | Brain,Embryo,Epithelium,Heart,Liver,PCR rescued clones, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.,sequence Caution:Translated as Gln.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151., |
