Price range: $268.00 through $328.00
Background:
dynamin 3(DNM3) Homo sapiens This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
| Size | 50μL/100μL |
| Target | DYN3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 95kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | DYN3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | DNM3 KIAA0820 |
| Protein Name | Dynamin-3 (Dynamin, testicular) (T-dynamin) |
| Other Name | |
| Species | Human |
| Gene ID | 26052 |
| Uniprot | Q9UQ16, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BZ98, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q08877 |
| Cellular Localization | Cytoplasm . Cytoplasm, cytoskeleton . Microtubule-associated. . |
| Tissue Expression | Brain,Kidney, |
| Signaling_pathway | Organismal Systems >> Nervous system >> Synaptic vesicle cycle;Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway |
| Research Areas | >>Phospholipase D signaling pathway; / >>Endocytosis; / >>Synaptic vesicle cycle; / >>Endocrine and other factor-regulated calcium reabsorption; / >>Bacterial invasion of epithelial cells |
| Function | Catalytic activity:GTP + H(2)O = GDP + phosphate.,Function:Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,similarity:Contains 1 PH domain.,subcellular location:Microtubule-associated., |
