SKU: WP11538 Categories: ,

Cdc40 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11538-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCdc40
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)66kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDC40. AA range:179-228
SpecificityCdc40 Polyclonal Antibody detects endogenous levels of Cdc40 protein.
Gene NameCDC40
Protein NamePre-mRNA-processing factor 17
Other NameCDC40; / EHB3; / PRP17; / PRPF17; / Pre-mRNA-processing factor 17; / Cell division cycle 40 homolog; / EH-binding protein 3; / Ehb3; / PRP17 homolog; / hPRP17
SpeciesHuman
Gene ID51362
UniprotO60508,
Species.1Mouse
Gene ID.171713
Uniprot.1Q9DC48
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Nucleus speckle .
Tissue ExpressionBrain,Cervix carcinoma,Colon,Colon epithelium,Epithelium,Trachea,
Signaling_pathway
Research Areas>>Spliceosome
FunctionFunction:Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.,similarity:Contains 7 WD repeats.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,
Please login to post questions
Back to Top
Product has been added to your cart