Price range: $268.00 through $328.00
Background:
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | Connexin-45 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Connexin-45. AA range:312-361 |
| Specificity | Connexin-45 Polyclonal Antibody detects endogenous levels of Connexin-45 protein. |
| Gene Name | GJC1 |
| Protein Name | Gap junction gamma-1 protein |
| Other Name | GJC1; / GJA7; / Gap junction gamma-1 protein; / Connexin-45; / Cx45; / Gap junction alpha-7 protein |
| Species | Human |
| Gene ID | 10052 |
| Uniprot | P36383, |
| Species.1 | Mouse |
| Gene ID.1 | 14615 |
| Uniprot.1 | P28229, |
| Species.2 | Rat |
| Gene ID.2 | 266706 |
| Uniprot.2 | A4GG66 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Tissue Expression | Testis,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Gamma-type subfamily.,subunit:A connexon is composed of a hexamer of connexins., |
