SKU: WP11830 Categories: ,

CTDSP1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11830-100
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Product details

Background:

CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],

Specifications

Size50μL/100μL
TargetCTDSP1
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)30kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CTDSP1. AA range:1-50
SpecificityCTDSP1 Polyclonal Antibody detects endogenous levels of CTDSP1 protein.
Gene NameCTDSP1
Protein NameCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Other NameCTDSP1; / NIF3; / NLIIF; / SCP1; / Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; / Nuclear LIM interactor-interacting factor 3; / NLI-IF; / NLI-interacting factor 3; / Small C-terminal domain phosphatase 1; / SCP1; / Small CTD ph
SpeciesHuman
Gene ID58190
UniprotQ9GZU7,
Species.1Mouse
Gene ID.1227292
Uniprot.1P58466
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Colocalizes with RNA polymerase II.
Tissue ExpressionExpression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
Signaling_pathway
Research Areas
FunctionCatalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,similarity:Contains 1 FCP1 homology domain.,subunit:May interact with LDB1 .,tissue specificity:Ubiquitously expressed, with highest expression in spleen, lung and placenta.,
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