SKU: WP7938 Categories: ,

EFHC1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7938-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetEFHC1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)70kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human EFHC1
SpecificityThis antibody detects endogenous levels of EFHC1 at Human, Mouse
Gene NameEFHC1
Protein NameEF-hand domain-containing protein 1 (Myoclonin-1)
Other Name
SpeciesHuman
Gene ID114327
UniprotQ5JVL4,
Species.1Mouse
Gene ID.171877
Uniprot.1Q9D9T8
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole .
Tissue ExpressionWidely expressed. Not detected in lymphocytes.
Signaling_pathway
Research Areas
FunctionMicrotubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization . Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration . May enhance calcium influx through CACNA1E and stimulate programmed cell death .
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