Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human EFHC1
Specificity
This antibody detects endogenous levels of EFHC1 at Human, Mouse
Gene Name
EFHC1
Protein Name
EF-hand domain-containing protein 1 (Myoclonin-1)
Other Name
Species
Human
Gene ID
114327
Uniprot
Q5JVL4,
Species.1
Mouse
Gene ID.1
71877
Uniprot.1
Q9D9T8
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole .
Tissue Expression
Widely expressed. Not detected in lymphocytes.
Signaling_pathway
Research Areas
Function
Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization . Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration . May enhance calcium influx through CACNA1E and stimulate programmed cell death .