Product details
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FLII rabbit pAb
Ucallm_WP8969-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FLII |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 140kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FLII |
| Specificity | This antibody detects endogenous levels of FLII at Human, Mouse |
| Gene Name | FLII FLIL |
| Protein Name | Protein flightless-1 homolog |
| Other Name | |
| Species | Human |
| Gene ID | 2314 |
| Uniprot | Q13045, |
| Species.1 | Mouse |
| Gene ID.1 | 14248 |
| Uniprot.1 | Q9JJ28 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, focal adhesion . Colocalizes to actin-rich structures in blastocysts and, together with HRAS, RHOA and CDC42, in migrating fibroblasts. Localizes to centrosomes (By similarity). . |
| Tissue Expression | Strongest expression in skeletal muscle with high expression also in the heart and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. |
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