SKU: WP7599 Categories: ,

IFT74 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7599-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetIFT74
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)66kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human IFT74
SpecificityThis antibody detects endogenous levels of IFT74 at Human, Mouse
Gene NameIFT74 CCDC2 CMG1
Protein NameIntraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2)
Other Name
SpeciesHuman
Gene ID80173
UniprotQ96LB3,
Species.1Mouse
Gene ID.167694
Uniprot.1Q8BKE9
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell projection, cilium. Cytoplasmic vesicle. Localizes along primary cilia at interphase and around the basal body/centriole at interphase and mitosis.
Tissue ExpressionHighly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen.
Signaling_pathway
Research Areas
FunctionComponent of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.
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