Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human IFT74
Specificity
This antibody detects endogenous levels of IFT74 at Human, Mouse
Gene Name
IFT74 CCDC2 CMG1
Protein Name
Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2)
Other Name
Species
Human
Gene ID
80173
Uniprot
Q96LB3,
Species.1
Mouse
Gene ID.1
67694
Uniprot.1
Q8BKE9
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell projection, cilium. Cytoplasmic vesicle. Localizes along primary cilia at interphase and around the basal body/centriole at interphase and mitosis.
Tissue Expression
Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen.
Signaling_pathway
Research Areas
Function
Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.