Name: IL-1F8 Polyclonal Antibody
SKU: WP15528
Price: 268 USD
Availability: InStock

IL-1F8 Polyclonal Antibody

Ucallm_WP15528-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP15528-100

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Product details

Background:

The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	IL-1F8
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	19kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL36B. AA range:111-160
Specificity	IL-1F8 Polyclonal Antibody detects endogenous levels of IL-1F8 protein.
Gene Name	IL36B
Protein Name	Interleukin-36 beta
Other Name	IL36B; / IL1F8; / IL1H2; / Interleukin-36 beta; / FIL1 eta; / Interleukin-1 eta; / IL-1 eta; / Interleukin-1 family member 8; / IL-1F8; / Interleukin-1 homolog 2; / IL-1H2
Species	Human
Gene ID	27177
Uniprot	Q9NZH7,
Species.1	Mouse
Gene ID.1	69677
Uniprot.1	Q9D6Z6
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .
Tissue Expression	Expression at low levels in tonsil, bone marrow, heart, placenta, lung, testis and colon but not in any hematopoietic cell lines. Not detected in adipose tissue. Expressed at higher levels in psoriatic plaques than in symptomless psoriatic skin or healthy control skin. Increased levels are not detected in inflamed joint tissue.
Signaling_pathway	Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas	>>Cytokine-cytokine receptor interaction
Function	online information:Interleukin-1 entry,similarity:Belongs to the IL-1 family.,tissue specificity:Expression at low levels in tonsil, bone marrow, heart, placenta, lung, testis and colon but not in other tissues or in any hematopoietic cell lines.,

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IL-1F8 Polyclonal Antibody

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IL-1F8 Polyclonal Antibody

Product details

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