SKU: WP4047 Categories: ,

IMPCT rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4047-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetIMPCT
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)35kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human IMPCT AA range: 123-173
SpecificityThis antibody detects endogenous levels of IMPCT at Human/Mouse/Rat
Gene NameIMPACT
Protein NameIMPCT
Other Name
SpeciesHuman
Gene ID55364
UniprotQ9P2X3,
Species.1Mouse
Gene ID.116210
Uniprot.1O55091,
Species.2Rat
Gene ID.2497198
Uniprot.2Q5GFD9
Cellular LocalizationCytoplasm .
Tissue ExpressionWidely expressed. Expressed at high level in brain.
Signaling_pathway
Research Areas
FunctionFunction:Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis.,miscellaneous:In contrast to the mouse or rabbit ortholog, the IMPACT locus is not imprinted in human.,similarity:Belongs to the IMPACT family.,similarity:Contains 1 RWD domain.,subunit:Interacts with GCN1/GCN1L1.,tissue specificity:Widely expressed. Expressed at high level in brain.,
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