Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human IRF2BP1
Specificity
This antibody detects endogenous levels of IRF2BP1 at Human, Mouse
Gene Name
IRF2BP1
Protein Name
Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 6.3.2.-)
Other Name
Species
Human
Gene ID
26145
Uniprot
Q8IU81,
Species.1
Mouse
Gene ID.1
272359
Uniprot.1
Q8R3Y8
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus .
Tissue Expression
Signaling_pathway
Research Areas
Function
Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.