Price range: $268.00 through $328.00
Background:
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | LGR6 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF |
| MW(Calculated) | |
| MW(Observed) | 104kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; IF 1:200-1:1000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LGR6. AA range:471-520 |
| Specificity | LGR6 Polyclonal Antibody detects endogenous levels of LGR6 protein. |
| Gene Name | LGR6 |
| Protein Name | Leucine-rich repeat-containing G-protein coupled receptor 6 |
| Other Name | LGR6; / Leucine-rich repeat-containing G-protein coupled receptor 6 |
| Species | Human |
| Gene ID | 59352 |
| Uniprot | Q9HBX8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q3UVD5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Mammary gland, |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Wnt signaling pathway |
| Research Areas | >>Wnt signaling pathway |
| Function | Function:Orphan receptor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 16 LRR (leucine-rich) repeats., |
