Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human LRCH1
Specificity
This antibody detects endogenous levels of LRCH1 at Human, Mouse
Gene Name
LRCH1 CHDC1 KIAA1016
Protein Name
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Other Name
Species
Human
Gene ID
23143
Uniprot
Q9Y2L9,
Species.1
Mouse
Gene ID.1
380916
Uniprot.1
P62046
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm .
Tissue Expression
Signaling_pathway
Research Areas
Function
Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.