LZTS2 rabbit pAb
Ucallm_WP6617-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | LZTS2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 74kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human LZTS2 |
| Specificity | This antibody detects endogenous levels of LZTS2 at Human, Mouse,Rat |
| Gene Name | LZTS2 KIAA1813 LAPSER1 |
| Protein Name | Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1) |
| Other Name | |
| Species | Human |
| Gene ID | 84445 |
| Uniprot | Q9BRK4, |
| Species.1 | Mouse |
| Gene ID.1 | 226154 |
| Uniprot.1 | Q91YU6, |
| Species.2 | Rat |
| Gene ID.2 | 365468 |
| Uniprot.2 | Q3LUD4 |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis. |
| Tissue Expression | Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon. |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Wnt signaling pathway |
| Research Areas | |
| Function | Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. |
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