MAGE-C1 [ABT251] mouse mAb
Product details
Background:
This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | MAGE-C1 |
| Reactivity | Human |
| Applications | IHC, ELISA |
| MW(Calculated) | 124kD |
| MW(Observed) | 180kD |
| Host Species | Mouse |
| Isotype | IgG2b,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-400; ELISA 1:500-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMM251 |
| Immunogen | Synthesized peptide derived from human MAGE-C1 AA range: 700-800 |
| Specificity | The antibody can specifically recognize human MAGE-C1 protein. |
| Gene Name | MAGEC1 |
| Protein Name | MAGE-C1 |
| Other Name | Melanoma-associated antigen C1; / Cancer/testis antigen 7.1; / CT7.1; / MAGE-C1 antigen |
| Species | Human |
| Gene ID | 9947 |
| Uniprot | O60732 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasmic |
| Tissue Expression | Expressed in testis and in tumors of a wide variety of histologic types. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 MAGE domain.,tissue specificity:Expressed in testis and in tumors of a wide variety of histologic types., |
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