SKU: WP4176 Categories: ,

MBOA7 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4176-100
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Product details

Background:

This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009],

Specifications

Size50μL/100μL
TargetMBOA7
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)52kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human MBOA7 AA range: 293-343
SpecificityThis antibody detects endogenous levels of MBOA7 at Human/Mouse
Gene NameMBOAT7 BB1 LENG4 OACT7
Protein NameMBOA7
Other Name
SpeciesHuman
Gene ID79143
UniprotQ96N66,
Species.1Mouse
Gene ID.177582
Uniprot.1Q8CHK3
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein . Localized in specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. .
Tissue ExpressionOverexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium.
Signaling_pathway
Research Areas>>Glycerophospholipid metabolism
FunctionCatalytic activity:Acyl-CoA + 1-acyl-sn-glycero-3-phosphatidylinositol = CoA + 1,2-diacyl-sn-glycero-3-phosphatidylinositol.,enzyme regulation:Activity is inhibited by thimerosal.,Function:Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.,pathway:Lipid metabolism; phospholipid metabolism.,similarity:Belongs to the membrane-bound acyltransferase family.,tissue specificity:Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium.,
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