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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/Relaxin Receptor 3 Polyclonal Antibody
SKU: WP14246 Categories: ,

Relaxin Receptor 3 Polyclonal Antibody

Ucallm_WP14246-50

Price range: $268.00 through $328.00

SKU: WP14246-100
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Product details

Background:

function:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,

Specifications

Size50μL/100μL
TargetRelaxin Receptor 3
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC
MW(Calculated)
MW(Observed)51kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human RXFP3. AA range:161-210
SpecificityRelaxin Receptor 3 Polyclonal Antibody detects endogenous levels of Relaxin Receptor 3 protein.
Gene NameRXFP3
Protein NameRelaxin-3 receptor 1
Other NameRXFP3; / RLN3R1; / SALPR; / Relaxin-3 receptor 1; / RLN3 receptor 1; / G protein-coupled receptor SALPR; / G-protein coupled receptor GPCR135; / Relaxin family peptide receptor 3; / Somatostatin- and angiotensin-like peptide receptor
SpeciesHuman
Gene ID51289
UniprotQ9NSD7,
Species.1Mouse
Gene ID.1239336
Uniprot.1Q8BGE9
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue ExpressionExpressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Signaling_pathwayOrganismal Systems >> Endocrine system >> Relaxin signaling pathway
Research Areas>>Neuroactive ligand-receptor interaction; / >>Relaxin signaling pathway
FunctionFunction:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,
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