SKU: WP17922 Categories: ,

RPR1A rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17922-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetRPRD1A
ReactivityHuman, Mouse
ApplicationsIHC, WB
MW(Calculated)34kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human C-ternal RPR1A
SpecificityThis antibody detects endogenous levels of RPR1A at Human, Mouse
Gene NameRPRD1A P15RS
Protein NameRegulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)
Other NameRegulation of nuclear pre-mRNA domain-containing protein 1A; / Cyclin-dependent kinase inhibitor 2B-related protein; / p15INK4B-related protein
SpeciesHuman
Gene ID55197
UniprotQ96P16,
Species.1Mouse
Gene ID.1225283
Uniprot.1Q8VDS4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
FunctionInteracts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
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