WB 1:500-2000; IHC 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C-ternal RPR1A
Specificity
This antibody detects endogenous levels of RPR1A at Human, Mouse
Gene Name
RPRD1A P15RS
Protein Name
Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)
Other Name
Regulation of nuclear pre-mRNA domain-containing protein 1A; / Cyclin-dependent kinase inhibitor 2B-related protein; / p15INK4B-related protein
Species
Human
Gene ID
55197
Uniprot
Q96P16,
Species.1
Mouse
Gene ID.1
225283
Uniprot.1
Q8VDS4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.