Price range: $268.00 through $328.00
Background:
SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008],
| Target | SIKE1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 22kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Sequence | |
| Specificity | SIKE1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | SIKE1 SIKE |
| Protein Name | Suppressor of IKBKE 1 (Suppressor of IKK-epsilon) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 80143 |
| Uniprot | Q9BRV8, |
| Species.1 | Mouse |
| Gene ID-2 | |
| Uniprot.1 | Q9CPR7, |
| Species.2 | Rat |
| Gene ID-3 | |
| Uniprot.2 | Q5FWT9 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008], |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and leukocytes. Present in all cell lines tested (at protein level). |
| Signaling_pathway | Organismal Systems >> Immune system >> RIG-I-like receptor signaling pathway |
| Research Areas | >>RIG-I-like receptor signaling pathway |
| Function | |
| RRID |
