Price range: $268.00 through $328.00
Background:
function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1., similarity:Contains 4 WD repeats., subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.,
| Size | 50μL/100μL |
| Target | TFIIIC110 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 100kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TF3C2. AA range:71-120 |
| Specificity | TFIIIC110 Polyclonal Antibody detects endogenous levels of TFIIIC110 protein. |
| Gene Name | GTF3C2 |
| Protein Name | General transcription factor 3C polypeptide 2 |
| Other Name | GTF3C2; / KIAA0011; / General transcription factor 3C polypeptide 2; / TF3C-beta; / Transcription factor IIIC 110 kDa subunit; / TFIIIC 110 kDa subunit; / TFIIIC110; / Transcription factor IIIC subunit beta |
| Species | Human |
| Gene ID | 2976 |
| Uniprot | Q8WUA4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BL74 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | Bone marrow,Brain,Colon,Epithelium, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.,similarity:Contains 4 WD repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6., |
