Name: TID1 rabbit pAb
SKU: WP8812
Price: 268 USD
Availability: InStock

TID1 rabbit pAb

Ucallm_WP8812-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP8812-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	DNAJA3
Reactivity	Human, Mouse
Applications	WB
MW(Calculated)	53kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human TID1
Specificity	This antibody detects endogenous levels of TID1 at Human, Mouse
Gene Name	DNAJA3 HCA57 TID1
Protein Name	DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Other Name
Species	Human
Gene ID	9093
Uniprot	Q96EY1,
Species.1	Mouse
Gene ID.1	83945
Uniprot.1	Q99M87
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Mitochondrion matrix. Cytoplasm, cytosol . Cell junction, synapse, postsynaptic cell membrane; Peripheral membrane protein . Recruited to the postsynaptic cell membrane of the neuromuscular junction through interaction with MUSK. .
Tissue Expression	Widely expressed with highest levels in heart, liver, lung and skeletal muscles. Also expressed in keratinocytes.
Signaling_pathway
Research Areas
Function	Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.