SKU: WP7477 Categories: ,

TMEM25 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7477-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTMEM25
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)40kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TMEM25
SpecificityThis antibody detects endogenous levels of TMEM25 at Human, Mouse
Gene NameTMEM25 UNQ2531/PRO6030
Protein NameTransmembrane protein 25
Other Name
SpeciesHuman
Gene ID84866
UniprotQ86YD3,
Species.1Mouse
Gene ID.171687
Uniprot.1Q9DCF1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization[Isoform 1]: Cell membrane; Single-pass type I membrane protein .; [Isoform 4]: Cell membrane; Single-pass type I membrane protein .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .; Late endosome . Lysosome .
Tissue ExpressionExpressed throughout the brain with higher levels in the pyramidal cell layer of the hippocampal CA1 and CA3 regions. Also highly expressed within the hippocampal dentate gyrus region and cerebellum and in scattered neurons in the cerebral cortex.
Signaling_pathway
Research Areas
FunctionIn neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.
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