Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TMEM25
Specificity
This antibody detects endogenous levels of TMEM25 at Human, Mouse
Gene Name
TMEM25 UNQ2531/PRO6030
Protein Name
Transmembrane protein 25
Other Name
Species
Human
Gene ID
84866
Uniprot
Q86YD3,
Species.1
Mouse
Gene ID.1
71687
Uniprot.1
Q9DCF1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
[Isoform 1]: Cell membrane; Single-pass type I membrane protein .; [Isoform 4]: Cell membrane; Single-pass type I membrane protein .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .; Late endosome . Lysosome .
Tissue Expression
Expressed throughout the brain with higher levels in the pyramidal cell layer of the hippocampal CA1 and CA3 regions. Also highly expressed within the hippocampal dentate gyrus region and cerebellum and in scattered neurons in the cerebral cortex.
Signaling_pathway
Research Areas
Function
In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.