Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TMEM5
Specificity
This antibody detects endogenous levels of TMEM5 at Human, Mouse
Gene Name
TMEM5
Protein Name
Transmembrane protein 5
Other Name
Species
Human
Gene ID
10329
Uniprot
Q9Y2B1,
Species.1
Mouse
Gene ID.1
216395
Uniprot.1
Q8VDX6
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Golgi apparatus membrane; Single-pass type II membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
Function
Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan (Probable). Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (Probable).