TMEM74 (Transmembrane Protein 74) is a Protein Coding gene. An important paralog of this gene is TMEM74B. Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction.
Specifications
Size
50μL/100μL
Target
TMM74
Reactivity
Human, Mouse
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
33kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human protein . at AA range: 181-230
Specificity
TMM74 Polyclonal Antibody detects endogenous levels of protein.
Gene Name
TMEM74
Protein Name
Transmembrane protein 74
Other Name
Species
Human
Gene ID
157753
Uniprot
Q96NL1,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q8BQU7
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Lysosome membrane; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein .