Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TRMT10A
Specificity
This antibody detects endogenous levels of TRMT10A at Human, Mouse,Rat
Gene Name
TRMT10A RG9MTD2
Protein Name
tRNA methyltransferase 10 homolog A (RNA (guanine-9-)-methyltransferase domain-containing protein 2)
Other Name
Species
Human
Gene ID
93587
Uniprot
Q8TBZ6,
Species.1
Mouse
Gene ID.1
108943
Uniprot.1
Q8C1Z8,
Species.2
Rat
Gene ID.2
295496
Uniprot.2
Q4KLI2
Cellular Localization
Nucleus . Nucleus, nucleolus .
Tissue Expression
Expressed in embryonic and fetal brain. It is expressed throughout the dorsal telencephalon at 8 and 11 weeks of gestation, with highest expression in ventricular zone and marginal zone. Detected in cerebellar cortex and nuclei, but not in dorsal telencephalon, at later stages.
Signaling_pathway
Research Areas
Function
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs . Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs .