TSLP rabbit pAb
Product details
Background:
function:Cytokine that induces the release of T cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells., induction:Released by primary epithelial cells in response to certain microbial products, physical injury, or inflammatory cytokines., subunit:Interacts with a receptor composed of CRLF2 and IL7R., tissue specificity:Expressed in a number of tissues including heart, liver and prostate.,
Specifications
| Size | 50μL/100μL |
| Target | TSLP |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | 17kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TSLP AA range: 91-140 |
| Specificity | This antibody detects endogenous levels of Human TSLP |
| Gene Name | TSLP |
| Protein Name | TSLP |
| Other Name | Thymic stromal lymphopoietin |
| Species | Human |
| Gene ID | 85480 |
| Uniprot | Q969D9, |
| Species.1 | Mouse |
| Gene ID.1 | 53603 |
| Uniprot.1 | Q9JIE6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction |
| Research Areas | >>Cytokine-cytokine receptor interaction; / >>JAK-STAT signaling pathway |
| Function |
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