TSPAN33 rabbit pAb
Ucallm_WP7224-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TSPAN33 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 31kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TSPAN33 |
| Specificity | This antibody detects endogenous levels of TSPAN33 at Human, Mouse |
| Gene Name | TSPAN33 PEN |
| Protein Name | Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane) |
| Other Name | |
| Species | Human |
| Gene ID | 340348 |
| Uniprot | Q86UF1, |
| Species.1 | Mouse |
| Gene ID.1 | 232670 |
| Uniprot.1 | Q8R3S2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Cell junction, adherens junction . Cytoplasm . Is localized to zonula adherens by PLEKHA7 by a PDZD11-dependent interaction. . |
| Tissue Expression | Predominantly expressed in erythroblasts. |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 . Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity . Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11-dependent manner, with the zonula adherens protein PLEKHA7 . |
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