U-Blot® c-Kit(CD117) hIgG1 Reference Antibody (Barbio)
UcallM
$999.00
Product details
Background：c-Kit, also known as CD117, is an important cell surface protein expressed in stem cells and various types of mature cells in humans and other animals. Encoded by the c-Kit gene, the c-Kit protein plays a role in cell proliferation, differentiation, and survival by binding with the cytokine SCF (stem cell factor). Mutations and abnormal expressions of the c-Kit gene have been associated with various diseases including tumors, cardiovascular diseases, and immune system disorders. Research on the c-Kit gene can aid scientists in better understanding its functions in cell biology and pathophysiology, offering new insights for diagnosis and treatment of related diseases.
Specifications
| Target | c-Kit(CD117) |
| Reactivity | |
| Applications | Flow Cytometry |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Human |
| Isotype | IgG1 |
| Conjugate/Modification | Unconjugated |
| Modification | |
| Recommended Dilution Ratio | |
| Formulation Buffer | Phosphate-buffered solution, pH 7.2-7.4. |
| Source | |
| Purification | |
| Purity | > 95% as determined by SDS-PAGE |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -422℃ long term.Avoid repeated freeze-thaw. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | barzolvolimab |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene Name | |
| Protein Name | |
| Other Name | C-Kit, CD117, MASTC, PBT, SCFR |
| Species | |
| Gene ID | |
| Uniprot | |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | |
| RRID |
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