VCX3 rabbit pAb
Ucallm_WP17220-50
Price range: $268.00 through $328.00
Product details
Background:
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | VCX3 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 20kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human VCX3 AA range: 40-90 |
| Specificity | This antibody detects endogenous levels of VCX3 at Human |
| Gene Name | VCX3A VCX3 VCX8R VCXA |
| Protein Name | VCX3 |
| Other Name | |
| Species | Human |
| Gene ID | 51481 |
| Uniprot | Q9NNX9 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | nucleus,nucleolus, |
| Tissue Expression | Expressed exclusively in testis. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:Defects in VCX3A are associated with some forms of X-linked nonspecific mental retardation.,Function:May mediate a process in spermatogenesis or may play a role in sex ratio distortion.,similarity:Belongs to the VCX/VCY family.,tissue specificity:Expressed exclusively in testis., |
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