SKU: WP8769 Categories: ,

ZNF658 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8769-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetZNF658
ReactivityHuman
ApplicationsWB
MW(Calculated)116kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ZNF658
SpecificityThis antibody detects endogenous levels of ZNF658 at Human
Gene NameZNF658
Protein NameZinc finger protein 658
Other Name
SpeciesHuman
Gene ID26149
UniprotQ5TYW1
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue Expression
Signaling_pathway
Research Areas
FunctionMediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.
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