SKU: WP8769 Categories: ,

ZNF658 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8769-100
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Product details

Background:

Specifications

TargetZNF658
ReactivityHuman
ApplicationsWB
MW(Calculated)116kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ZNF658
Sequence
SpecificityThis antibody detects endogenous levels of ZNF658 at Human
Gene NameZNF658
Protein NameZinc finger protein 658
Other Name
SpeciesHuman
Gene ID-126149
UniprotQ5TYW1
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationNucleus .
Tissue Expression
Signaling_pathway
Research Areas
FunctionMediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.
RRID
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