SKU: WP12006 Categories: ,

DHHC-9 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12006-100
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Product details

Background:

This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010],

Specifications

Size50μL/100μL
TargetDHHC-9
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)41kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ZDHHC9. AA range:315-364
SpecificityDHHC-9 Polyclonal Antibody detects endogenous levels of DHHC-9 protein.
Gene NameZDHHC9
Protein NamePalmitoyltransferase ZDHHC9
Other NameZDHHC9; / CXorf11; / ZDHHC10; / ZNF379; / ZNF380; / CGI-89; / Palmitoyltransferase ZDHHC9; / Zinc finger DHHC domain-containing protein 9; / DHHC-9; / DHHC9; / Zinc finger protein 379; / Zinc finger protein 380
SpeciesHuman
Gene ID51114
UniprotQ9Y397,
Species.1Mouse
Gene ID.1208884
Uniprot.1P59268
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein .
Tissue ExpressionHighly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.
Signaling_pathway
Research Areas
FunctionCatalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,Domain:The DHHC domain is required for palmitoyltransferase activity.,Function:The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.,similarity:Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.,similarity:Contains 1 DHHC-type zinc finger.,subunit:Interacts with GOLGA7.,tissue specificity:Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.,
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