SKU: WP0896 Categories: ,

ABCAA Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0896-100
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Product details

Background:

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetABCAA
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)169kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 1100-1180
SpecificityABCAA Polyclonal Antibody detects endogenous levels of protein.
Gene NameABCA10
Protein NameATP-binding cassette sub-family A member 10
Other Name
SpeciesHuman
Gene ID10349
UniprotQ8WWZ4
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Multi-pass membrane protein .
Tissue ExpressionWidely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract.
Signaling_pathway
Research Areas>>ABC transporters
FunctionFunction:Probable transporter which may play a role in macrophage lipid homeostasis.,induction:Down-regulated by cholesterol loading of macrophages.,similarity:Belongs to the ABC transporter family. ABCA subfamily.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract.,
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