Price range: $268.00 through $328.00
Background:
This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010],
| Target | ACTT1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 41kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ACTT1 AA range: 241-291 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ACTT1 at Human/Mouse/Rat |
| Gene Name | ACTRT1 ARPT1 HSD27 |
| Protein Name | ACTT1 |
| Other Name | |
| Species | Human |
| Gene ID-1 | 139741 |
| Uniprot | Q8TDG2, |
| Species.1 | Mouse |
| Gene ID-2 | 73360 |
| Uniprot.1 | Q9D9J3, |
| Species.2 | Rat |
| Gene ID-3 | 302796 |
| Uniprot.2 | Q5XIK1 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010], |
| Cellular Localization | Cytoplasm, cytoskeleton . Cytoplasm . Nucleus . Both detected in the nucleus and cytoplasm, localizes to the nucleus where it binds chromatin upon stimulation of the Hedgehog pathway. . |
| Tissue Expression | In skin, expressed in the basal, spinous and granular layers of the epidermis. Also expressed in hair follicles, sebaceaous glands, eccrine sweat glands and semen. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the actin family., |
| RRID |
