SKU: WP11492 Categories: ,

CD2BP2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11492-100
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Product details

Background:

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],

Specifications

Size50μL/100μL
TargetCD2BP2
ReactivityHuman, Monkey
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)50kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150
SpecificityCD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.
Gene NameCD2BP2
Protein NameCD2 antigen cytoplasmic tail-binding protein 2
Other NameCD2BP2; / KIAA1178; / CD2 antigen cytoplasmic tail-binding protein 2; / CD2 cytoplasmic domain-binding protein 2; / CD2 tail-binding protein 2
SpeciesHuman
Gene ID10421
UniprotO95400,
Species.1Mouse
Gene ID.1
Uniprot.1Q9CWK3
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm. Nucleus. Predominantly nuclear.
Tissue ExpressionAorta,Brain,Epithelium,Liver,Lung,
Signaling_pathway
Research Areas
Functionsimilarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain.,
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