SKU: WP1208 Categories: ,

HXC8 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1208-100
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Product details

Background:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetHXC8
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)26kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityHXC8 Polyclonal Antibody detects endogenous levels of protein.
Gene NameHOXC8 HOX3A
Protein NameHomeobox protein Hox-C8 (Homeobox protein Hox-3A)
Other Name
SpeciesHuman
Gene ID3224
UniprotP31273,
Species.1Mouse
Gene ID.1
Uniprot.1P09025,
Species.2Rat
Gene ID.2
Uniprot.2P18866
Cellular LocalizationNucleus.
Tissue ExpressionEye,
Signaling_pathway
Research Areas
FunctionFunction:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with SMAD1 and HOMEZ.,
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