Product details
Background:
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IFT25 rabbit pAb
Ucallm_WP6071-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | IFT25 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 16kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IFT25 |
| Specificity | This antibody detects endogenous levels of IFT25 at Human, Mouse |
| Gene Name | HSPB11 C1orf41 HSPC034 |
| Protein Name | Heat shock protein beta-11 (Hspb11) (Placental protein 25) (PP25) |
| Other Name | |
| Species | Human |
| Gene ID | 51668 |
| Uniprot | Q9Y547, |
| Species.1 | Mouse |
| Gene ID.1 | 72938 |
| Uniprot.1 | Q9D6H2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell projection, cilium . |
| Tissue Expression | Detected in placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity). |
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