SKU: WP3272 Categories: ,

IMMT Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP3272-100
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Product details

Background:

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 22114354, PubMed: 25781180).

Specifications

TargetMitofilin
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)83kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
Sequence
SpecificityIMMT Polyclonal Antibody detects endogenous levels of protein.
Gene NameIMMT HMP MINOS2 PIG4 PIG52
Protein NameMitochondrial inner membrane protein (Cell proliferation-inducing gene 4/52 protein) (Mitofilin) (p87/89)
Other Name
SpeciesHuman
Gene ID-110989
UniprotQ16891,
Species.1Mouse
Gene ID-2
Uniprot.1Q8CAQ8,
Species.2Rat
Gene ID-3
Uniprot.2Q3KR86
Organism-4
Gene ID-4
SwissProt-4
BackgroundComponent of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 22114354, PubMed: 25781180).
Cellular LocalizationMitochondrion inner membrane; Single-pass membrane protein . Mitochondrion .
Tissue ExpressionB-cell lymphoma,Bone marrow,Brain,Cajal-Retzius cell,Cervix,Colon e
Signaling_pathway
Research Areas
Function
RRID
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