SKU: WP7987 Categories: ,

IMPAD1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7987-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetBPNT2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)39kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human IMPAD1
SpecificityThis antibody detects endogenous levels of IMPAD1 at Human, Mouse,Rat
Gene NameIMPAD1 IMPA3
Protein NameInositol monophosphatase 3 (IMP 3) (IMPase 3) (Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase) (Golgi-resident PAP phosphatase) (gPAPP) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3)
Other Name
SpeciesHuman
Gene ID54928
UniprotQ9NX62,
Species.1Mouse
Gene ID.1242291
Uniprot.1Q80V26,
Species.2Rat
Gene ID.2100910881
Uniprot.2D4AD37
Cellular LocalizationGolgi apparatus . Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein . The catalytic core is predicted to reside within the Golgi lumen. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionExhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4.
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