Product details
Background:
KR121 rabbit pAb
Ucallm_WP16934-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KR121 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF |
| MW(Calculated) | 11kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KR121 AA range: 22-72 |
| Specificity | This antibody detects endogenous levels of KR121 at Human/Mouse |
| Gene Name | KRTAP12-1 KAP12.1 KRTAP12.1 |
| Protein Name | KR121 |
| Other Name | |
| Species | Human |
| Gene ID | 353332 |
| Uniprot | P59990, |
| Species.1 | Mouse |
| Gene ID.1 | 16694 |
| Uniprot.1 | Q9Z287 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | keratin filament, |
| Tissue Expression | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 12 family.,subunit:Interacts with hair keratins.,tissue specificity:Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues., |
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