Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human MAGI1
Specificity
This antibody detects endogenous levels of MAGI1 at Human, Mouse,Rat
Gene Name
MAGI1 AIP3 BAIAP1 BAP1 TNRC19
Protein Name
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Other Name
Species
Human
Gene ID
9223
Uniprot
Q96QZ7,
Species.1
Mouse
Gene ID.1
14924
Uniprot.1
Q6RHR9,
Species.2
Rat
Gene ID.2
500261
Uniprot.2
Q4L1J4
Cellular Localization
Cell junction, tight junction . Cell membrane; Peripheral membrane protein . Localizes to epithelial cells tight junctions.
Tissue Expression
Widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain.
Signaling_pathway
Cellular Processes >> Cellular community - eukaryotes >> Tight junction;Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Research Areas
Function
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).