SKU: WM1271 Categories: ,

Nrf2 [PTR2557] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1271-50
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Product details

Background:
nuclear factor, erythroid 2 like 2(NFE2L2) Homo sapiens This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],

Specifications

Size50μL/100μL
TargetNrf2
ReactivityHuman,Mouse,Rat,
ApplicationsWB,IF,ELISA
MW(Calculated)68kD
MW(Observed)100kD
Host SpeciesMouse
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationProtein G
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRMMR2557
ImmunogenSynthesized peptide derived from human Nrf2 AA range: 300-400
SpecificityThis antibody detects endogenous levels of Nrf2 protein.
Gene NameNFE2L2 NRF2
Protein NameNuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Other NameNuclear factor erythroid 2-related factor 2;NF-E2-related factor 2;NFE2-related factor 2;HEBP1;Nuclear factor, erythroid derived 2, like 2;
SpeciesHuman
Gene ID4780
UniprotQ16236
Species.1Mouse
Gene ID.118024
Uniprot.1Q60795
Species.2Rat
Gene ID.283619
Uniprot.2O54968
Cellular LocalizationCytoplasmic, Nuclear
Tissue Expression
Signaling_pathway
Research Areas
Function
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