Name: RPN2 rabbit pAb
SKU: WP6943
Price: 268 USD
Availability: InStock

RPN2 rabbit pAb

Ucallm_WP6943-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP6943-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	RPN2
Reactivity	Human, Mouse, Rat
Applications	WB
MW(Calculated)	69kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human RPN2
Specificity	This antibody detects endogenous levels of RPN2 at Human, Mouse,Rat
Gene Name	RPN2
Protein Name	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2)
Other Name
Species	Human
Gene ID	6185
Uniprot	P04844,
Species.1	Mouse
Gene ID.1	20014
Uniprot.1	Q9DBG6,
Species.2	Rat
Gene ID.2	64701
Uniprot.2	P25235
Cellular Localization	Endoplasmic reticulum . Endoplasmic reticulum membrane; Multi-pass membrane protein .
Tissue Expression	Expressed in all tissues tested.
Signaling_pathway	Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum
Research Areas
Function	Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation . N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.