Name: RS7 Polyclonal Antibody
SKU: WP0795
Price: 268 USD
Availability: InStock

RS7 Polyclonal Antibody

Ucallm_WP0795-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP0795-100

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Product details

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	RS7
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	21kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 50-130
Specificity	RS7 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	RPS7
Protein Name	40S ribosomal protein S7
Other Name
Species	Human
Gene ID	6201
Uniprot	P62081,
Species.1	Mouse
Gene ID.1
Uniprot.1	P62082,
Species.2	Rat
Gene ID.2
Uniprot.2	P62083
Cellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with NEK6 in the centrosome. .
Tissue Expression	Brain,Liver,Lung,Placenta,Spleen,
Signaling_pathway
Research Areas	>>Ribosome; / >>Coronavirus disease - COVID-19
Function	Disease:Defects in RPS7 are the cause of Diamond-Blackfan anemia type 8 (DBA8) [MIM:612563]. DBA8 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.,Function:Required for rRNA maturation.,similarity:Belongs to the ribosomal protein S7e family.,subunit:Binds IPO9 with high affinity.,