SKU: WP6249 Categories: ,

SLC38A1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6249-100
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Product details

Background:

Specifications

TargetSLC38A1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)54kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SLC38A1
Sequence
SpecificityThis antibody detects endogenous levels of SLC38A1 at Human, Mouse,Rat
Gene NameSLC38A1 ATA1 NAT2 SAT1 SNAT1
Protein NameSodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System N amino acid transporter 1)
Other Name
SpeciesHuman
Gene ID-181539
UniprotQ9H2H9,
Species.1Mouse
Gene ID-2105727
Uniprot.1Q8K2P7,
Species.2Rat
Gene ID-3170567
Uniprot.2Q9JM15
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationCell membrane; Multi-pass membrane protein . Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain (By similarity). .
Tissue ExpressionExpressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis.
Signaling_pathwayOrganismal Systems >> Nervous system >> Glutamatergic synapse
Research Areas
FunctionFunctions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.
RRID
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