Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SLC38A1
Sequence
Specificity
This antibody detects endogenous levels of SLC38A1 at Human, Mouse,Rat
Gene Name
SLC38A1 ATA1 NAT2 SAT1 SNAT1
Protein Name
Sodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System N amino acid transporter 1)
Other Name
Species
Human
Gene ID-1
81539
Uniprot
Q9H2H9,
Species.1
Mouse
Gene ID-2
105727
Uniprot.1
Q8K2P7,
Species.2
Rat
Gene ID-3
170567
Uniprot.2
Q9JM15
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular Localization
Cell membrane; Multi-pass membrane protein . Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain (By similarity). .
Tissue Expression
Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis.
Signaling_pathway
Organismal Systems >> Nervous system >> Glutamatergic synapse
Research Areas
Function
Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.