Product details
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SPC24 rabbit pAb
Ucallm_WP6782-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SPC24 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 22kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SPC24 |
| Specificity | This antibody detects endogenous levels of SPC24 at Human, Mouse |
| Gene Name | SPC24 SPBC24 |
| Protein Name | Kinetochore protein Spc24 (hSpc24) |
| Other Name | |
| Species | Human |
| Gene ID | 147841 |
| Uniprot | Q8NBT2, |
| Species.1 | Mouse |
| Gene ID.1 | 67629 |
| Uniprot.1 | Q9D083 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Chromosome, centromere, kinetochore . Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity . Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore . The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules . |
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