Price range: $268.00 through $328.00
Background:
This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
| Size | 50μL/100μL |
| Target | TAUT |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 70kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC6A6. AA range:561-610 |
| Specificity | TAUT Polyclonal Antibody detects endogenous levels of TAUT protein. |
| Gene Name | SLC6A6 |
| Protein Name | Sodium- and chloride-dependent taurine transporter |
| Other Name | SLC6A6; / Sodium- and chloride-dependent taurine transporter; / Solute carrier family 6 member 6 |
| Species | Human |
| Gene ID | 6533 |
| Uniprot | P31641, |
| Species.1 | Mouse |
| Gene ID.1 | 21366 |
| Uniprot.1 | O35316, |
| Species.2 | Rat |
| Gene ID.2 | 29464 |
| Uniprot.2 | P31643 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Required for the uptake of taurine.,PTM:Down-regulated upon Ser-322 phosphorylation.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family., |
