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TWSG1 rabbit pAb
Ucallm_WP8396-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TWSG1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 25kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TWSG1 |
| Specificity | This antibody detects endogenous levels of TWSG1 at Human, Mouse |
| Gene Name | TWSG1 TSG PSEC0250 |
| Protein Name | Twisted gastrulation protein homolog 1 |
| Other Name | |
| Species | Human |
| Gene ID | 57045 |
| Uniprot | Q9GZX9, |
| Species.1 | Mouse |
| Gene ID.1 | 65960 |
| Uniprot.1 | Q9EP52 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity). |
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