Price range: $268.00 through $328.00
Background:
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | YY1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 230-310 |
| Specificity | TYY1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | YY1 INO80S |
| Protein Name | Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1) |
| Other Name | TYY1; / Transcriptional repressor protein YY1; / Delta transcription factor; / INO80 complex subunit S; / NF-E1; / Yin and yang 1; / YY-1 |
| Species | Human |
| Gene ID | 7528 |
| Uniprot | P25490, |
| Species.1 | Mouse |
| Gene ID.1 | 22632 |
| Uniprot.1 | Q00899 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus matrix . Associated with the nuclear matrix. |
| Tissue Expression | Brain,Epithelium,Foreskin,Lymph, |
| Signaling_pathway | Genetic Information Processing >> Chromosome >> ATP-dependent chromatin remodeling |
| Research Areas | |
| Function | Function:Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. May play an important role in development and differentiation. The function of YY1 as an activator or a repressor is specified by the presence of other proteins. For example it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence.,similarity:Belongs to the YY transcription factor family.,similarity:Contains 4 C2H2-type zinc fingers.,subcellular location:Associated with the nuclear matrix.,subunit:Interacts with YAF2 through the region encompassing the first and second zinc fingers. Interacts with INO80., |
