Product details
Background:
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UBE2C rabbit pAb
Ucallm_WP6235-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | UBE2C |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 20kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human UBE2C |
| Specificity | This antibody detects endogenous levels of UBE2C at Human, Mouse |
| Gene Name | UBE2C UBCH10 |
| Protein Name | Ubiquitin-conjugating enzyme E2 C (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C) |
| Other Name | |
| Species | Human |
| Gene ID | 11065 |
| Uniprot | O00762, |
| Species.1 | Mouse |
| Gene ID.1 | 68612 |
| Uniprot.1 | Q9D1C1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> Ubiquitin mediated proteolysis |
| Research Areas | |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. |
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